Beschrijving

Reviews aspects of GABA-A receptor function, as well as the properties of a variety of other important inhibitory proteins, such as GABA-C receptors and G-protein coupled receptors including neuropeptides. This title covers Glycine receptors and potassium channels.

Within the central and peripheral nervous systems of animals, including man, inhibition is crucial to counterbalance excitatory neurotransmission, which is predominantly mediated by glutamate and its receptors. Although, particularly in brain, much of this inhibition is provided by classical post-synaptic GABAA receptors, many other proteins and mechanisms regulate excitation. These exist both to \